Platelet GPIIb/IIIa receptor blockers for failed thrombolysis in acute myocardial infarction, alone or as adjunct to other rescue therapies
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چکیده
منابع مشابه
Platelet GPIIb/IIIa receptor blockers for failed thrombolysis in acute myocardial infarction, alone or as adjunct to other rescue therapies.
Early and complete restoration of myocardial blood flow is the therapeutic goal for treatment of patients with acute myocardial infarction (MI). After fibrinolytic therapy patients who fail to achieve Thrombolysis in Myocardial Infarction (TIMI) grade 3 epicardial blood flow are at high risk of death and congestive heart failure. With currently available thrombolytic therapies less than two-thi...
متن کامل'Rescue' after failed thrombolysis for acute myocardial infarction.
Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical assessment in individual patients often suggests that reperfusion has not occu...
متن کاملPredictors of Failed Thrombolysis in Acute Myocardial Infarction
Background & objectives: Acute myocardial infarction (AMI) is becoming increasingly important problem in developing countries, and thrombolysis is the main modality of treatment here. About 2550% of patients fail to achieve successful reperfusion and these patients have poor prognosis. Since alternative modes of reperfusion are available, it is important to identify them. This study was aimed a...
متن کاملThrombolysis and adjunctive therapies in acute myocardial infarction.
Thrombolysis and percutaneous transluminal angioplasty represent the cornerstone of the pharmacologic treatment of and the interventional approach to patients with myocardial infarction (MI). They are very effective. However, they are hampered by some critical limitations. Therefore, alternatives to standard thrombolytic therapy have been developed. Platelet glycoprotein (GP) IIb/IIIa blockade ...
متن کاملThrombolysis for Acute Myocardial Infarction
Indlvldual studies of patency rates and left ventricular (LV) function after thrombolysis have generally been limited by small numbers of observations, wide confidence intervals, and limRed numbers of time points. To obtain a more reliable estimate of patterns of patency and LV ejection fraction, a systematic overview of anglographic studies was performed after itira= venous thrombolytic therap...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2002
ISSN: 0195-668X
DOI: 10.1053/euhj.2002.3273